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CDK7 inhibition augments response to multidrug chemotherapy in pancreatic cancer

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with a dismal prognosis. Although combined treatment with gemcitabine and albumin-bound paclitaxel has improved the prognosis of PDAC, both intrinsic and acquired chemoresistance remain as severe hurtles towards improved pro...

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Detalles Bibliográficos
Autores principales:	Zeng, Siyuan, Lan, Bin, Ren, Xiaofan, Zhang, Shuman, Schreyer, Daniel, Eckstein, Markus, Yang, Hai, Britzen-Laurent, Nathalie, Dahl, Andreas, Mukhopadhyay, Debabrata, Chang, David, Kutschick, Isabella, Pfeffer, Susanne, Bailey, Peter, Biankin, Andrew, Grützmann, Robert, Pilarsky, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364549/ https://www.ncbi.nlm.nih.gov/pubmed/35945614 http://dx.doi.org/10.1186/s13046-022-02443-w

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