Dopamine receptor D2 regulates GLUA1-containing AMPA receptor trafficking and central sensitization through the PI3K signaling pathway in a male rat model of chronic migraine

BACKGROUND: The pathogenesis of chronic migraine remains unresolved. Recent studies have affirmed the contribution of GLUA1-containing AMPA receptors to chronic migraine. The dopamine D2 receptor, a member of G protein-coupled receptor superfamily, has been proven to have an analgesic effect on path...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Lei, Ming, Wen, Qianwen, Zhang, Dunke, Qin, Guangcheng, Zhou, Jiying, Chen, Lixue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364568/
https://www.ncbi.nlm.nih.gov/pubmed/35948867
http://dx.doi.org/10.1186/s10194-022-01469-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364568/
https://www.ncbi.nlm.nih.gov/pubmed/35948867
http://dx.doi.org/10.1186/s10194-022-01469-x

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