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Dopamine receptor D2 regulates GLUA1-containing AMPA receptor trafficking and central sensitization through the PI3K signaling pathway in a male rat model of chronic migraine
BACKGROUND: The pathogenesis of chronic migraine remains unresolved. Recent studies have affirmed the contribution of GLUA1-containing AMPA receptors to chronic migraine. The dopamine D2 receptor, a member of G protein-coupled receptor superfamily, has been proven to have an analgesic effect on path...
Autores principales: | Zhang, Wei, Lei, Ming, Wen, Qianwen, Zhang, Dunke, Qin, Guangcheng, Zhou, Jiying, Chen, Lixue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Milan
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364568/ https://www.ncbi.nlm.nih.gov/pubmed/35948867 http://dx.doi.org/10.1186/s10194-022-01469-x |
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