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The HIV Latency Reversal Agent HODHBt Enhances NK Cell Effector and Memory-Like Functions by Increasing Interleukin-15-Mediated STAT Activation

Elimination of human immunodeficiency virus (HIV) reservoirs is a critical endpoint to eradicate HIV. One therapeutic intervention against latent HIV is “shock and kill.” This strategy is based on the transcriptional activation of latent HIV with a latency-reversing agent (LRA) with the consequent k...

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Detalles Bibliográficos
Autores principales: Macedo, Amanda B., Levinger, Callie, Nguyen, Bryan N., Richard, Jonathan, Gupta, Mamta, Cruz, Conrad Russell Y., Finzi, Andrés, Chiappinelli, Katherine B., Crandall, Keith A., Bosque, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364794/
https://www.ncbi.nlm.nih.gov/pubmed/35867565
http://dx.doi.org/10.1128/jvi.00372-22