B cells in the balance: Offsetting self-reactivity avoidance with protection against foreign

Antibodies are theoretically limitless in their diversity and specificity to foreign antigens; however they are constrained by the need to avoid binding to self. Germinal centers (GC) allow diversification and maturation of the antibody response towards the foreign antigen. While self-tolerance mech...

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Detalles Bibliográficos
Autores principales: Young, Clara, Lau, Angelica W. Y., Burnett, Deborah L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364820/
https://www.ncbi.nlm.nih.gov/pubmed/35967439
http://dx.doi.org/10.3389/fimmu.2022.951385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364820/
https://www.ncbi.nlm.nih.gov/pubmed/35967439
http://dx.doi.org/10.3389/fimmu.2022.951385

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