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B cells in the balance: Offsetting self-reactivity avoidance with protection against foreign
Antibodies are theoretically limitless in their diversity and specificity to foreign antigens; however they are constrained by the need to avoid binding to self. Germinal centers (GC) allow diversification and maturation of the antibody response towards the foreign antigen. While self-tolerance mech...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364820/ https://www.ncbi.nlm.nih.gov/pubmed/35967439 http://dx.doi.org/10.3389/fimmu.2022.951385 |