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How insulin-like growth factor I binds to a hybrid insulin receptor type 1 insulin-like growth factor receptor

Monomers of the insulin receptor and type 1 insulin-like growth factor receptor (IGF-1R) can combine stochastically to form heterodimeric hybrid receptors. These hybrid receptors display ligand binding and signaling properties that differ from those of the homodimeric receptors. Here, we describe th...

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Detalles Bibliográficos
Autores principales: Xu, Yibin, Margetts, Mai B., Venugopal, Hari, Menting, John G., Kirk, Nicholas S., Croll, Tristan I., Delaine, Carlie, Forbes, Briony E., Lawrence, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364964/
https://www.ncbi.nlm.nih.gov/pubmed/35660159
http://dx.doi.org/10.1016/j.str.2022.05.007