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Dissecting the roles of the Tuberin protein in the subcellular localization of the G2/M Cyclin, Cyclin B1

Tuberin is a major component of the protein regulatory complex known as the Tuberous Sclerosis Complex and plays a crucial role in cell cycle progression and protein synthesis. Mutations in the Tuberin gene, TSC2, lead to the formation of benign tumors in many organ systems and causes the Tuberous S...

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Detalles Bibliográficos
Autores principales: Pillon, Adam, Dare-Shih, Jessica, Fong, Jackie, Fidalgo da Silva, Elizabeth, Porter, Lisa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365131/
https://www.ncbi.nlm.nih.gov/pubmed/35947627
http://dx.doi.org/10.1371/journal.pone.0272741