Interaction-based Mendelian randomization with measured and unmeasured gene-by-covariate interactions

Studies leveraging gene-environment (GxE) interactions within Mendelian randomization (MR) analyses have prompted the emergence of two similar methodologies: MR-GxE and MR-GENIUS. Such methods are attractive in allowing for pleiotropic bias to be corrected when using individual instruments. Specific...

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Detalles Bibliográficos
Autores principales: Spiller, Wes, Hartwig, Fernando Pires, Sanderson, Eleanor, Davey Smith, George, Bowden, Jack
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365161/
https://www.ncbi.nlm.nih.gov/pubmed/35947639
http://dx.doi.org/10.1371/journal.pone.0271933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365161/
https://www.ncbi.nlm.nih.gov/pubmed/35947639
http://dx.doi.org/10.1371/journal.pone.0271933

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