Newly synthesized mRNA escapes translational repression during the acute phase of the mammalian unfolded protein response

Endoplasmic Reticulum (ER) stress, caused by the accumulation of misfolded proteins in the ER, elicits a homeostatic mechanism known as the Unfolded Protein Response (UPR). The UPR reprograms gene expression to promote adaptation to chronic ER stress. The UPR comprises an acute phase involving inhib...

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Detalles Bibliográficos
Autores principales: Alzahrani, Mohammed R., Guan, Bo-Jhih, Zagore, Leah L., Wu, Jing, Chen, Chien-Wen, Licatalosi, Donny D., Baker, Kristian E., Hatzoglou, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365188/
https://www.ncbi.nlm.nih.gov/pubmed/35947624
http://dx.doi.org/10.1371/journal.pone.0271695

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365188/
https://www.ncbi.nlm.nih.gov/pubmed/35947624
http://dx.doi.org/10.1371/journal.pone.0271695

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