Cargando…

Newly synthesized mRNA escapes translational repression during the acute phase of the mammalian unfolded protein response

Endoplasmic Reticulum (ER) stress, caused by the accumulation of misfolded proteins in the ER, elicits a homeostatic mechanism known as the Unfolded Protein Response (UPR). The UPR reprograms gene expression to promote adaptation to chronic ER stress. The UPR comprises an acute phase involving inhib...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alzahrani, Mohammed R., Guan, Bo-Jhih, Zagore, Leah L., Wu, Jing, Chen, Chien-Wen, Licatalosi, Donny D., Baker, Kristian E., Hatzoglou, Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365188/ https://www.ncbi.nlm.nih.gov/pubmed/35947624 http://dx.doi.org/10.1371/journal.pone.0271695

Ejemplares similares

DAZL Regulates Germ Cell Survival through a Network of PolyA-Proximal mRNA Interactions
por: Zagore, Leah L., et al.
Publicado: (2018)

Efficient GFP‐labeling and analysis of spermatogenic cells using the IRG transgene and flow cytometry
por: Zagore, Leah L., et al.
Publicado: (2019)

The kinetic landscape of an RNA binding protein in cells
por: Sharma, Deepak, et al.
Publicado: (2021)

The helicase Ded1p controls use of near-cognate translation initiation codons in 5′UTRs
por: Guenther, Ulf-Peter, et al.
Publicado: (2018)

Argonaute High-Throughput Sequencing of RNAs Isolated by Cross-Linking Immunoprecipitation Reveals a Snapshot of miRNA Gene Regulation in the Mammalian Retina
por: Sundermeier, Thomas R., et al.
Publicado: (2014)

Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cells
Publicado: (1995)

Single channel properties of newly synthesized acetylcholine receptors following denervation of mammalian skeletal muscle
Publicado: (1987)

Co-translational mechanisms of quality control of newly synthesized polypeptides
por: Gandin, Valentina, et al.
Publicado: (2014)

Cytomegalovirus Downregulates IRE1 to Repress the Unfolded Protein Response
por: Stahl, Sebastian, et al.
Publicado: (2013)

RITA requires eIF2α-dependent modulation of mRNA translation for its anti-cancer activity
por: Ristau, Johannes, et al.
Publicado: (2019)

The different axes of the mammalian mitochondrial unfolded protein response
por: Münch, Christian
Publicado: (2018)

Quantitative analysis of mRNA translation in mammalian spermatogenic cells with sucrose and Nycodenz gradients
por: Kleene, Kenneth C, et al.
Publicado: (2010)

mRNA for N-Bak, a neuron-specific BH3-only splice isoform of Bak, escapes nonsense-mediated decay and is translationally repressed in the neurons
por: Jakobson, M, et al.
Publicado: (2012)

Staphylococcus aureus synthesizes adenosine to escape host immune responses
por: Thammavongsa, Vilasack, et al.
Publicado: (2009)

Integrative analysis of genome‐wide lncRNA and mRNA expression in newly synthesized Brassica hexaploids
por: Wang, Ruihua, et al.
Publicado: (2018)

MART-10, a newly synthesized vitamin D analog, represses metastatic potential of head and neck squamous carcinoma cells
por: Yang, Shih-Wei, et al.
Publicado: (2016)

Roles of mitochondrial unfolded protein response in mammalian stem cells
por: Gu, Li-Fang, et al.
Publicado: (2021)

mRNA Targeting to Endoplasmic Reticulum Precedes Ago Protein Interaction and MicroRNA (miRNA)-mediated Translation Repression in Mammalian Cells
por: Barman, Bahnisikha, et al.
Publicado: (2015)

DUBs “found in translation”: USP15 controls stability of newly synthesized REST
por: Xirodimas, Dimitris P
Publicado: (2013)

Translational repression of thymidylate synthase by targeting its mRNA
por: Garg, Divita, et al.
Publicado: (2013)

Hfq‐dependent mRNA unfolding promotes sRNA‐based inhibition of translation
por: Hoekzema, Mirthe, et al.
Publicado: (2019)

The many routes to regulating mRNA translation
por: Baker, Kristian E, et al.
Publicado: (2006)

The porphyrin TmPyP4 unfolds the extremely stable G-quadruplex in MT3-MMP mRNA and alleviates its repressive effect to enhance translation in eukaryotic cells
por: Morris, Mark J., et al.
Publicado: (2012)

THE DISTRIBUTION OF NEWLY SYNTHESIZED DNA IN MITOTIC DIVISION
por: Plaut, Walter, et al.
Publicado: (1956)

Fishing for newly synthesized proteins with phosphonate-handles
por: Kleinpenning, Fleur, et al.
Publicado: (2020)

An unfolded protein-induced conformational switch activates mammalian IRE1
por: Karagöz, G Elif, et al.
Publicado: (2017)

Structure and dynamics of the quaternary hunchback mRNA translation repression complex
por: Macošek, Jakub, et al.
Publicado: (2021)

Histone Acetyl Transferase 1 Is Essential for Mammalian Development, Genome Stability, and the Processing of Newly Synthesized Histones H3 and H4
por: Nagarajan, Prabakaran, et al.
Publicado: (2013)

microRNA-Mediated Messenger RNA Deadenylation Contributes to Translational Repression in Mammalian Cells
por: Beilharz, Traude H., et al.
Publicado: (2009)

Misfolding and aggregation of newly synthesized proteins in the endoplasmic reticulum
Publicado: (1992)

Newly synthesized acetylcholine receptors are located in the Golgi apparatus
Publicado: (1978)

Association of newly synthesized islet prohormones with intracellular membranes
Publicado: (1984)

Antioxidant and Antitumor Activities of Newly Synthesized Hesperetin Derivatives
por: Zhong, Guanlin, et al.
Publicado: (2022)

Crystal structures of three newly synthesized flavanone hydrazones
por: Yennawar, Hemant P., et al.
Publicado: (2023)

Distinct transcriptional responses elicited by unfolded nuclear or cytoplasmic protein in mammalian cells
por: Miyazaki, Yusuke, et al.
Publicado: (2015)

Functional analysis of the mammalian RNA ligase for IRE1 in the unfolded protein response
por: Poothong, Juthakorn, et al.
Publicado: (2017)

Oral Pathogen Porphyromonas gingivalis Can Escape Phagocytosis of Mammalian Macrophages
por: Werheim, Erik R., et al.
Publicado: (2020)

Fine-tuning of microRNA-mediated repression of mRNA by splicing-regulated and highly repressive microRNA recognition element
por: Wu, Cheng-Tao, et al.
Publicado: (2013)

Repression of viral gene expression and replication by the unfolded protein response effector XBP1u
por: Hinte, Florian, et al.
Publicado: (2020)

Assessment of Selective mRNA Translation in Mammalian Cells by Polysome Profiling
por: Faye, Mame Daro, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_2sp2ao01icv6mqg23bmo1f8nl0