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Amlodipine Improves Spinal Cord Injury Repair by Inhibiting Motoneuronal Apoptosis Through Autophagy Upregulation

The effect of amlodipine (AM) on spinal cord injury (SCI) and autophagy was researched by establishing ventral spinal cord cells (VSC4.1) oxygen and glucose deprivation model and SCI mice model. OBJECTIVE. To determine the neuroprotective effects of AM by upregulating autophagy during SCI repair. SU...

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Detalles Bibliográficos
Autores principales: Huang, Yang, Ren, Hao, Gao, Xiang, Cai, Danyang, Shan, Huajian, Bai, Jinyu, Sheng, Lei, Jin, Yong, Zhou, Xiaozhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365253/
https://www.ncbi.nlm.nih.gov/pubmed/34923548
http://dx.doi.org/10.1097/BRS.0000000000004310