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Primary specification of blastocyst trophectoderm by scRNA-seq: New insights into embryo implantation

Mechanisms of implantation such as determination of the attachment pole, fetal-maternal communication, and underlying causes of implantation failure are largely unexplored. Here, we performed single-cell RNA sequencing on peri-implantation embryos from both humans and mice to explore trophectoderm (...

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Detalles Bibliográficos
Autores principales: Liu, Dandan, Chen, Yidong, Ren, Yixin, Yuan, Peng, Wang, Nan, Liu, Qiang, Yang, Cen, Yan, Zhiqiang, Yang, Ming, Wang, Jing, Lian, Ying, Yan, Jie, Zhai, Fan, Nie, Yanli, Zhu, Xiaohui, Chen, Yuan, Li, Rong, Chang, Hsun-Ming, Leung, Peter C. K., Qiao, Jie, Yan, Liying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365277/
https://www.ncbi.nlm.nih.gov/pubmed/35947672
http://dx.doi.org/10.1126/sciadv.abj3725