Single-cell multiomics sequencing reveals the reprogramming defects in embryos generated by round spermatid injection

Round spermatid injection (ROSI) technique holds great promise for clinical treatment of a proportion of infertile men. However, the compromised developmental potential of ROSI embryos largely limits the clinical application, and the mechanisms are not fully understood. Here, we describe the transcr...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Zhou, Cai, Gao, Shuai, Song, Xiuling, Yang, Xinyan, Fan, Jiaqi, Ren, Shaofang, Ma, Linzi, Zhao, Jiexiang, Cui, Manman, Song, Ke, Wang, Mei, Li, Chaohui, Zheng, Yi, Luo, Fang, Miao, Kai, Bai, Xiaochun, Hutchins, Andrew P., Li, Lin, Chang, Gang, Zhao, Xiao-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365279/
https://www.ncbi.nlm.nih.gov/pubmed/35947654
http://dx.doi.org/10.1126/sciadv.abm3976

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365279/
https://www.ncbi.nlm.nih.gov/pubmed/35947654
http://dx.doi.org/10.1126/sciadv.abm3976

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