Single-cell multiomics sequencing reveals the reprogramming defects in embryos generated by round spermatid injection

Round spermatid injection (ROSI) technique holds great promise for clinical treatment of a proportion of infertile men. However, the compromised developmental potential of ROSI embryos largely limits the clinical application, and the mechanisms are not fully understood. Here, we describe the transcr...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Jing, Zhou, Cai, Gao, Shuai, Song, Xiuling, Yang, Xinyan, Fan, Jiaqi, Ren, Shaofang, Ma, Linzi, Zhao, Jiexiang, Cui, Manman, Song, Ke, Wang, Mei, Li, Chaohui, Zheng, Yi, Luo, Fang, Miao, Kai, Bai, Xiaochun, Hutchins, Andrew P., Li, Lin, Chang, Gang, Zhao, Xiao-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365279/
https://www.ncbi.nlm.nih.gov/pubmed/35947654
http://dx.doi.org/10.1126/sciadv.abm3976

Ejemplares similares

Ejemplares similares