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Disruption of the circadian clock drives Apc loss of heterozygosity to accelerate colorectal cancer
An alarming rise in young onset colorectal cancer (CRC) has been reported; however, the underlying molecular mechanism remains undefined. Suspected risk factors of young onset CRC include environmental aspects, such as lifestyle and dietary factors, which are known to affect the circadian clock. We...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365282/ https://www.ncbi.nlm.nih.gov/pubmed/35947664 http://dx.doi.org/10.1126/sciadv.abo2389 |