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Disruption of the circadian clock drives Apc loss of heterozygosity to accelerate colorectal cancer

An alarming rise in young onset colorectal cancer (CRC) has been reported; however, the underlying molecular mechanism remains undefined. Suspected risk factors of young onset CRC include environmental aspects, such as lifestyle and dietary factors, which are known to affect the circadian clock. We...

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Detalles Bibliográficos
Autores principales:	Chun, Sung Kook, Fortin, Bridget M., Fellows, Rachel C., Habowski, Amber N., Verlande, Amandine, Song, Wei A., Mahieu, Alisa L., Lefebvre, Austin E. Y. T., Sterrenberg, Jason N., Velez, Leandro M., Digman, Michelle A., Edwards, Robert A., Pannunzio, Nicholas R., Seldin, Marcus M., Waterman, Marian L., Masri, Selma
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365282/ https://www.ncbi.nlm.nih.gov/pubmed/35947664 http://dx.doi.org/10.1126/sciadv.abo2389

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