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Targeting Refractory Mantle Cell Lymphoma for Imaging and Therapy Using C-X-C Chemokine Receptor Type 4 Radioligands

PURPOSE: Mantle cell lymphoma (MCL) is associated with poor survival. The purpose of this study was to assess whether the C-X-C chemokine receptor type 4 (CXCR4) is a useful target for imaging and radioligand therapy of MCL, using a novel pair of radioligands, [(68)Ga]Ga and [(177)Lu]Lu-BL02. EXPERI...

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Detalles Bibliográficos
Autores principales: Kwon, Daniel, Takata, Katsuyoshi, Zhang, Zhengxing, Chong, Lauren, Fraser, Bryan, Zeisler, Jutta, Miyata-Takata, Tomoko, Merkens, Helen, Rousseau, Julie, Aoki, Tomohiro, Kuo, Hsiou-Ting, Tan, Ruiyan, Zhang, Chengcheng, Lau, Joseph, Villa, Diego, Uribe, Carlos F., Lin, Kuo-Shyan, Steidl, Christian, Benard, Francois
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365342/
https://www.ncbi.nlm.nih.gov/pubmed/35078860
http://dx.doi.org/10.1158/1078-0432.CCR-21-3284