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Safety and Activity of PolyPEPI1018 Combined with Maintenance Therapy in Metastatic Colorectal Cancer: an Open-Label, Multicenter, Phase Ib Study
PURPOSE: Although chemotherapy is standard of care for metastatic colorectal cancer (mCRC), immunotherapy has no role in microsatellite stable (MSS) mCRC, a “cold” tumor. PolyPEPI1018 is an off-the-shelf, multi-peptide vaccine derived from 7 tumor-associated antigens (TAA) frequently expressed in mC...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artigo Texto |
Idioma: | English |
Publicado em: |
American Association for Cancer Research
2022
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Assuntos: | |
Acesso em linha: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365360/ https://www.ncbi.nlm.nih.gov/pubmed/35472243 http://dx.doi.org/10.1158/1078-0432.CCR-22-0112 |