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Long-term Safety of Treatment with Autologous Mesenchymal Stem Cells in Patients with Radiation-Induced Xerostomia: Primary Results of the MESRIX Phase I/II Randomized Trial

PURPOSE: Mesenchymal stem/stromal cell therapy may reduce radiation-induced xerostomia. We investigated the long-term safety of autologous adipose tissue-derived mesenchymal stem/stromal cell (ASC) injections into the submandibular glands. EXPERIMENTAL DESIGN: An investigator-initiated, randomized,...

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Detalles Bibliográficos
Autores principales: Lynggaard, Charlotte Duch, Grønhøj, Christian, Jensen, Siri B., Christensen, Robin, Specht, Lena, Andersen, Elo, Andersen, Tobias T., Ciochon, Urszula M., Rathje, Gulla S., Hansen, Adam E., Stampe, Helene, Fischer-Nielsen, Anne, von Buchwald, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365378/
https://www.ncbi.nlm.nih.gov/pubmed/35486613
http://dx.doi.org/10.1158/1078-0432.CCR-21-4520