Aberrant Activation of Cell-Cycle–Related Kinases and the Potential Therapeutic Impact of PLK1 or CHEK1 Inhibition in Uterine Leiomyosarcoma

PURPOSE: Uterine leiomyosarcoma is among the most aggressive gynecological malignancies. No effective treatment strategies have been established. This study aimed to identify novel therapeutic targets for uterine leiomyosarcoma based on transcriptome analysis and assess the preclinical efficacy of n...

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Detalles Bibliográficos
Autores principales: Yoshida, Kosuke, Yokoi, Akira, Yamamoto, Tomofumi, Hayashi, Yusuke, Nakayama, Jun, Yokoi, Tsuyoshi, Yoshida, Hiroshi, Kato, Tomoyasu, Kajiyama, Hiroaki, Yamamoto, Yusuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Translational Cancer Mechanisms and Therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365385/
https://www.ncbi.nlm.nih.gov/pubmed/35302600
http://dx.doi.org/10.1158/1078-0432.CCR-22-0100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365385/
https://www.ncbi.nlm.nih.gov/pubmed/35302600
http://dx.doi.org/10.1158/1078-0432.CCR-22-0100

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