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Senescent preosteoclast secretome promotes metabolic syndrome associated osteoarthritis through cyclooxygenase 2

BACKGROUND: Metabolic syndrome–associated osteoarthritis (MetS-OA) is a distinct osteoarthritis phenotype defined by the coexistence of MetS or its individual components. Despite the high prevalence of MetS-OA, its pathogenic mechanisms are unclear. The aim of this study was to determine the role of...

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Detalles Bibliográficos
Autores principales: Su, Weiping, Liu, Guanqiao, Mohajer, Bahram, Wang, Jiekang, Shen, Alena, Zhang, Weixin, Liu, Bin, Guermazi, Ali, Gao, Peisong, Cao, Xu, Demehri, Shadpour, Wan, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365389/
https://www.ncbi.nlm.nih.gov/pubmed/35881544
http://dx.doi.org/10.7554/eLife.79773