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Large protein complex interfaces have evolved to promote cotranslational assembly

Assembly pathways of protein complexes should be precise and efficient to minimise misfolding and unwanted interactions with other proteins in the cell. One way to achieve this efficiency is by seeding assembly pathways during translation via the cotranslational assembly of subunits. While recent ev...

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Detalles Bibliográficos
Autores principales: Badonyi, Mihaly, Marsh, Joseph A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365393/
https://www.ncbi.nlm.nih.gov/pubmed/35899946
http://dx.doi.org/10.7554/eLife.79602