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Three-dimensional structure of kinetochore-fibers in human mitotic spindles

During cell division, kinetochore microtubules (KMTs) provide a physical linkage between the chromosomes and the rest of the spindle. KMTs in mammalian cells are organized into bundles, so-called kinetochore-fibers (k-fibers), but the ultrastructure of these fibers is currently not well characterize...

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Detalles Bibliográficos
Autores principales: Kiewisz, Robert, Fabig, Gunar, Conway, William, Baum, Daniel, Needleman, Daniel, Müller-Reichert, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365394/
https://www.ncbi.nlm.nih.gov/pubmed/35894209
http://dx.doi.org/10.7554/eLife.75459