Aging the brain: multi-region methylation principal component based clock in the context of Alzheimer’s disease

Alzheimer’s disease (AD) risk increases exponentially with age and is associated with multiple molecular hallmarks of aging, one of which is epigenetic alterations. Epigenetic age predictors based on 5’ cytosine methylation (DNAm), or epigenetic clocks, have previously suggested that epigenetic age...

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Detalles Bibliográficos
Autores principales: Thrush, Kyra L., Bennett, David A., Gaiteri, Christopher, Horvath, Steve, van Dyck, Christopher H., Higgins-Chen, Albert T., Levine, Morgan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365556/
https://www.ncbi.nlm.nih.gov/pubmed/35907208
http://dx.doi.org/10.18632/aging.204196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365556/
https://www.ncbi.nlm.nih.gov/pubmed/35907208
http://dx.doi.org/10.18632/aging.204196

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