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miR-21 upregulation exacerbates pressure overload-induced cardiac hypertrophy in aged hearts

Young and aging hearts undergo different remodeling post pressure overload, but the regulator that determines responses to pressure overload at different ages remains unknown. With an angiotensin II (Ang II)-induced hypertensive model, miR-21 knockout mice (miR-21(−/−)) were observed regarding the e...

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Detalles Bibliográficos
Autores principales: Chang, Wei-Ting, Shih, Jhih-Yuan, Lin, Yu-Wen, Huang, Tzu-Ling, Chen, Zhih-Cherng, Chen, Chi-Long, Chu, Jan-Show, Liu, Ping Yen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365557/
https://www.ncbi.nlm.nih.gov/pubmed/35907209
http://dx.doi.org/10.18632/aging.204194