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miR-21 upregulation exacerbates pressure overload-induced cardiac hypertrophy in aged hearts
Young and aging hearts undergo different remodeling post pressure overload, but the regulator that determines responses to pressure overload at different ages remains unknown. With an angiotensin II (Ang II)-induced hypertensive model, miR-21 knockout mice (miR-21(−/−)) were observed regarding the e...
Autores principales: | Chang, Wei-Ting, Shih, Jhih-Yuan, Lin, Yu-Wen, Huang, Tzu-Ling, Chen, Zhih-Cherng, Chen, Chi-Long, Chu, Jan-Show, Liu, Ping Yen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365557/ https://www.ncbi.nlm.nih.gov/pubmed/35907209 http://dx.doi.org/10.18632/aging.204194 |
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