Using multivariable Mendelian randomization to estimate the causal effect of bone mineral density on osteoarthritis risk, independently of body mass index

OBJECTIVES: Observational analyses suggest that high bone mineral density (BMD) is a risk factor for osteoarthritis (OA); it is unclear whether this represents a causal effect or shared aetiology and whether these relationships are body mass index (BMI)-independent. We performed bidirectional Mendel...

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Detalles Bibliográficos
Autores principales: Hartley, April, Sanderson, Eleanor, Granell, Raquel, Paternoster, Lavinia, Zheng, Jie, Smith, George Davey, Southam, Lorraine, Hatzikotoulas, Konstantinos, Boer, Cindy G, van Meurs, Joyce, Zeggini, Eleftheria, Gregson, Celia L, Tobias, Jon H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365636/
https://www.ncbi.nlm.nih.gov/pubmed/34897459
http://dx.doi.org/10.1093/ije/dyab251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365636/
https://www.ncbi.nlm.nih.gov/pubmed/34897459
http://dx.doi.org/10.1093/ije/dyab251

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