Seipin concentrates distinct neutral lipids via interactions with their acyl chain carboxyl esters

Lipid droplets (LDs) are essential for cellular lipid homeostasis by storing diverse neutral lipids (NLs), such as triacylglycerol (TAG), steryl esters (SE), and retinyl esters (RE). A proper assembly of TAG-containing LDs at the ER requires Seipin, a conserved protein often mutated in lipodystrophi...

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Detalles Bibliográficos
Autores principales: Renne, Mike F., Corey, Robin A., Ferreira, Joana Veríssimo, Stansfeld, Phillip J., Carvalho, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365673/
https://www.ncbi.nlm.nih.gov/pubmed/35938957
http://dx.doi.org/10.1083/jcb.202112068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365673/
https://www.ncbi.nlm.nih.gov/pubmed/35938957
http://dx.doi.org/10.1083/jcb.202112068

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