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Nanoscale organization of the MHC I peptide-loading complex in human dendritic cells

Dendritic cells (DCs) translate local innate immune responses into long-lasting adaptive immunity by priming antigen-specific T cells. Accordingly, there is an ample interest in exploiting DCs for therapeutic purposes, e.g., in personalized immunotherapies. Despite recent advances in elucidating mol...

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Detalles Bibliográficos
Autores principales: Koller, Nicole, Höllthaler, Philipp, Barends, Martina, Döring, Marius, Spahn, Christoph, Durán, Verónica, Costa, Bibiana, Becker, Jennifer, Heilemann, Mike, Kalinke, Ulrich, Tampé, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365725/
https://www.ncbi.nlm.nih.gov/pubmed/35947215
http://dx.doi.org/10.1007/s00018-022-04472-2