Karyotype engineering reveals spatio-temporal control of replication firing and gene contacts

Eukaryotic genomes vary in terms of size, chromosome number, and genetic complexity. Their temporal organization is complex, reflecting coordination between DNA folding and function. Here, we used fused karyotypes of budding yeast to characterize the effects of chromosome length on nuclear architect...

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Detalles Bibliográficos
Autores principales: Lazar-Stefanita, Luciana, Luo, Jingchuan, Montagne, Remi, Thierry, Agnes, Sun, Xiaoji, Mercy, Guillaume, Mozziconacci, Julien, Koszul, Romain, Boeke, Jef D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365758/
https://www.ncbi.nlm.nih.gov/pubmed/35983101
http://dx.doi.org/10.1016/j.xgen.2022.100163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365758/
https://www.ncbi.nlm.nih.gov/pubmed/35983101
http://dx.doi.org/10.1016/j.xgen.2022.100163

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