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Karyotype engineering reveals spatio-temporal control of replication firing and gene contacts
Eukaryotic genomes vary in terms of size, chromosome number, and genetic complexity. Their temporal organization is complex, reflecting coordination between DNA folding and function. Here, we used fused karyotypes of budding yeast to characterize the effects of chromosome length on nuclear architect...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365758/ https://www.ncbi.nlm.nih.gov/pubmed/35983101 http://dx.doi.org/10.1016/j.xgen.2022.100163 |