Molecular basis of MHC I quality control in the peptide loading complex

Major histocompatibility complex class I (MHC I) molecules are central to adaptive immunity. Their assembly, epitope selection, and antigen presentation are controlled by the MHC I glycan through a sophisticated network of chaperones and modifying enzymes. However, the mechanistic integration of the...

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Detalles Bibliográficos
Autores principales: Domnick, Alexander, Winter, Christian, Sušac, Lukas, Hennecke, Leon, Hensen, Mario, Zitzmann, Nicole, Trowitzsch, Simon, Thomas, Christoph, Tampé, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365787/
https://www.ncbi.nlm.nih.gov/pubmed/35948544
http://dx.doi.org/10.1038/s41467-022-32384-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365787/
https://www.ncbi.nlm.nih.gov/pubmed/35948544
http://dx.doi.org/10.1038/s41467-022-32384-z

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