Cargando…

Molecular basis of MHC I quality control in the peptide loading complex

Major histocompatibility complex class I (MHC I) molecules are central to adaptive immunity. Their assembly, epitope selection, and antigen presentation are controlled by the MHC I glycan through a sophisticated network of chaperones and modifying enzymes. However, the mechanistic integration of the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Domnick, Alexander, Winter, Christian, Sušac, Lukas, Hennecke, Leon, Hensen, Mario, Zitzmann, Nicole, Trowitzsch, Simon, Thomas, Christoph, Tampé, Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365787/ https://www.ncbi.nlm.nih.gov/pubmed/35948544 http://dx.doi.org/10.1038/s41467-022-32384-z

Ejemplares similares

Semisynthetic Viral Inhibitor for Light Control of the MHC I Peptide Loading Complex
por: Winter, Christian, et al.
Publicado: (2022)

Assembly of the MHC I peptide-loading complex determined by a conserved ionic lock-switch
por: Blees, Andreas, et al.
Publicado: (2015)

Viral immune evasins impact antigen presentation by allele-specific trapping of MHC I at the peptide-loading complex
por: Sethumadhavan, Sunesh, et al.
Publicado: (2022)

Structure of an MHC I–tapasin–ERp57 editing complex defines chaperone promiscuity
por: Müller, Ines Katharina, et al.
Publicado: (2022)

Nanoscale organization of the MHC I peptide-loading complex in human dendritic cells
por: Koller, Nicole, et al.
Publicado: (2022)

Dynamic interactome of the MHC I peptide loading complex in human dendritic cells
por: Barends, Martina, et al.
Publicado: (2023)

Light control of the peptide-loading complex synchronizes antigen translocation and MHC I trafficking
por: Brunnberg, Jamina, et al.
Publicado: (2021)

Proofreading of Peptide—MHC Complexes through Dynamic Multivalent Interactions
por: Thomas, Christoph, et al.
Publicado: (2017)

Molecular mechanism of peptide editing in the tapasin–MHC I complex
por: Fisette, Olivier, et al.
Publicado: (2016)

The ER folding sensor UGGT1 acts on TAPBPR-chaperoned peptide-free MHC I
por: Sagert, Lina, et al.
Publicado: (2023)

Direct evidence that the N-terminal extensions of the TAP complex act as autonomous interaction scaffolds for the assembly of the MHC I peptide-loading complex
por: Hulpke, Sabine, et al.
Publicado: (2012)

Structure of a fully assembled tumor-specific T cell receptor ligated by pMHC
por: Sušac, Lukas, et al.
Publicado: (2022)

A loop structure allows TAPBPR to exert its dual function as MHC I chaperone and peptide editor
por: Sagert, Lina, et al.
Publicado: (2020)

Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation
por: Jiang, Jiansheng, et al.
Publicado: (2022)

Structures of peptide-free and partially loaded MHC class I molecules reveal mechanisms of peptide selection
por: Anjanappa, Raghavendra, et al.
Publicado: (2020)

TAPBPR promotes antigen loading on MHC-I molecules using a peptide trap
por: McShan, Andrew C., et al.
Publicado: (2021)

A dual inhibition mechanism of herpesviral ICP47 arresting a conformationally thermostable TAP complex
por: Herbring, Valentina, et al.
Publicado: (2016)

Universal open MHC-I molecules for rapid peptide loading and enhanced complex stability across HLA allotypes
por: Sun, Yi, et al.
Publicado: (2023)

Phosphorylation-dependent interaction between antigenic peptides and MHC class I: a molecular basis for presentation of transformed self
por: Mohammed, Fiyaz, et al.
Publicado: (2008)

The MHC class I peptide repertoire is molded by the transcriptome
por: Fortier, Marie-Hélène, et al.
Publicado: (2008)

Scrutinizing MHC-I Binding Peptides and Their Limits of Variation
por: Koch, Christian P., et al.
Publicado: (2013)

Specific MHC-I Peptides Are Induced Using PROTACs
por: Jensen, Stephanie M., et al.
Publicado: (2018)

Whole genome duplications have provided teleosts with many roads to peptide loaded MHC class I molecules
por: Grimholt, Unni
Publicado: (2018)

Structural basis for ineffective T-cell responses to MHC anchor residue-improved “heteroclitic” peptides
por: Madura, Florian, et al.
Publicado: (2015)

The V beta complementarity determining region 1 of a major histocompatibility complex (MHC) class I-restricted T cell receptor is involved in the recognition of peptide/MHC I and superantigen/MHC II complex
Publicado: (1994)

Structural Allele-Specific Patterns Adopted by Epitopes in the MHC-I Cleft and Reconstruction of MHC:peptide Complexes to Cross-Reactivity Assessment
por: Antunes, Dinler A., et al.
Publicado: (2010)

A Peptide Filtering Relation Quantifies MHC Class I Peptide Optimization
por: Dalchau, Neil, et al.
Publicado: (2011)

Dynamically Driven Allostery in MHC Proteins: Peptide-Dependent Tuning of Class I MHC Global Flexibility
por: Ayres, Cory M., et al.
Publicado: (2019)

CapsNet-MHC predicts peptide-MHC class I binding based on capsule neural networks
por: Kalemati, Mahmood, et al.
Publicado: (2023)

Non-conventional sources of peptides presented by MHC class I
por: Starck, Shelley R., et al.
Publicado: (2011)

Prediction of MHC class I binding peptides, using SVMHC
por: Dönnes, Pierre, et al.
Publicado: (2002)

Effects of Peptide on NK Cell-Mediated MHC I Recognition
por: Cassidy, Sorcha A., et al.
Publicado: (2014)

Properties of MHC Class I Presented Peptides That Enhance Immunogenicity
por: Calis, Jorg J. A., et al.
Publicado: (2013)

Production and Thermal Exchange of Conditional Peptide‐MHC I Multimers
por: Luimstra, Jolien J., et al.
Publicado: (2019)

TCR Recognition of Peptide–MHC-I: Rule Makers and Breakers
por: Szeto, Christopher, et al.
Publicado: (2020)

Structural Basis for the Restoration of TCR Recognition of an MHC Allelic Variant by Peptide Secondary Anchor Substitution
por: Miley, Michael J., et al.
Publicado: (2004)

Most viral peptides displayed by class I MHC on infected cells are immunogenic
por: Croft, Nathan P., et al.
Publicado: (2019)

Improving peptide-MHC class I binding prediction for unbalanced datasets
por: Sales, Ana Paula, et al.
Publicado: (2008)

Identical peptides recognized by MHC class I- and II-restricted T cells
Publicado: (1989)

Class I MHC can present an endogenous peptide to cytotoxic T lymphocytes
Publicado: (1989)

Cannot write session to /tmp/vufind_sessions/sess_5ubg99rn6gi331o0rfbae9rahq