mTORC1 controls Golgi architecture and vesicle secretion by phosphorylation of SCYL1

The protein kinase mechanistic target of rapamycin complex 1 (mTORC1) is a master regulator of cell growth and proliferation, supporting anabolic reactions and inhibiting catabolic pathways like autophagy. Its hyperactivation is a frequent event in cancer promoting tumor cell proliferation. Several...

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Detalles Bibliográficos
Autores principales: Kaeser-Pebernard, Stéphanie, Vionnet, Christine, Mari, Muriel, Sankar, Devanarayanan Siva, Hu, Zehan, Roubaty, Carole, Martínez-Martínez, Esther, Zhao, Huiyuan, Spuch-Calvar, Miguel, Petri-Fink, Alke, Rainer, Gregor, Steinberg, Florian, Reggiori, Fulvio, Dengjel, Jörn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365812/
https://www.ncbi.nlm.nih.gov/pubmed/35948564
http://dx.doi.org/10.1038/s41467-022-32487-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365812/
https://www.ncbi.nlm.nih.gov/pubmed/35948564
http://dx.doi.org/10.1038/s41467-022-32487-7

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