PRC1-mediated epigenetic programming is required to generate the ovarian reserve

The ovarian reserve defines the female reproductive lifespan, which in humans spans decades due to robust maintenance of meiotic arrest in oocytes residing in primordial follicles. Epigenetic reprogramming, including DNA demethylation, accompanies meiotic entry, but the chromatin changes that underp...

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Detalles Bibliográficos
Autores principales: Hu, Mengwen, Yeh, Yu-Han, Munakata, Yasuhisa, Abe, Hironori, Sakashita, Akihiko, Maezawa, So, Vidal, Miguel, Koseki, Haruhiko, Hunter, Neil, Schultz, Richard M., Namekawa, Satoshi H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365831/
https://www.ncbi.nlm.nih.gov/pubmed/35948547
http://dx.doi.org/10.1038/s41467-022-31759-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365831/
https://www.ncbi.nlm.nih.gov/pubmed/35948547
http://dx.doi.org/10.1038/s41467-022-31759-6

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