Evidence for a HURP/EB free mixed-nucleotide zone in kinetochore-microtubules

Current models infer that the microtubule-based mitotic spindle is built from GDP-tubulin with small GTP caps at microtubule plus-ends, including those that attach to kinetochores, forming the kinetochore-fibres. Here we reveal that kinetochore-fibres additionally contain a dynamic mixed-nucleotide...

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Detalles Bibliográficos
Autores principales: Castrogiovanni, Cédric, Inchingolo, Alessio V., Harrison, Jonathan U., Dudka, Damian, Sen, Onur, Burroughs, Nigel J., McAinsh, Andrew D., Meraldi, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365851/
https://www.ncbi.nlm.nih.gov/pubmed/35948594
http://dx.doi.org/10.1038/s41467-022-32421-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365851/
https://www.ncbi.nlm.nih.gov/pubmed/35948594
http://dx.doi.org/10.1038/s41467-022-32421-x

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