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Evidence for a HURP/EB free mixed-nucleotide zone in kinetochore-microtubules
Current models infer that the microtubule-based mitotic spindle is built from GDP-tubulin with small GTP caps at microtubule plus-ends, including those that attach to kinetochores, forming the kinetochore-fibres. Here we reveal that kinetochore-fibres additionally contain a dynamic mixed-nucleotide...
Autores principales: | Castrogiovanni, Cédric, Inchingolo, Alessio V., Harrison, Jonathan U., Dudka, Damian, Sen, Onur, Burroughs, Nigel J., McAinsh, Andrew D., Meraldi, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365851/ https://www.ncbi.nlm.nih.gov/pubmed/35948594 http://dx.doi.org/10.1038/s41467-022-32421-x |
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