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Modulation of osteogenic differentiation by Escherichia coli-derived recombinant bone morphogenetic protein-2
Recombinant human bone morphogenetic protein-2 (rhBMP-2), a key regulator of osteogenesis, induces the differentiation of mesenchymal cells into cartilage or bone tissues. Early orthopedic and dental studies often used mammalian cell-derived rhBMP-2, especially Chinese hamster ovary (CHO) cells. How...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365917/ https://www.ncbi.nlm.nih.gov/pubmed/35947236 http://dx.doi.org/10.1186/s13568-022-01443-5 |