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Modulation of osteogenic differentiation by Escherichia coli-derived recombinant bone morphogenetic protein-2

Recombinant human bone morphogenetic protein-2 (rhBMP-2), a key regulator of osteogenesis, induces the differentiation of mesenchymal cells into cartilage or bone tissues. Early orthopedic and dental studies often used mammalian cell-derived rhBMP-2, especially Chinese hamster ovary (CHO) cells. How...

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Detalles Bibliográficos
Autores principales: Kim, Nam-Hyun, Jung, Seon-Kyong, Lee, Juno, Chang, Pahn-Shick, Kang, Seung-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365917/
https://www.ncbi.nlm.nih.gov/pubmed/35947236
http://dx.doi.org/10.1186/s13568-022-01443-5