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The Orexin receptors: Structural and anti-tumoral properties

At the end of the 20th century, two new neuropeptides (Orexin-A/hypocretin-1 and Orexin-B/hypocretins-2) expressed in hypothalamus as a prepro-orexins precursor, were discovered. These two neuropeptides interacted with two G protein-coupled receptor isoforms named OX1R and OX2R. The orexins/OX recep...

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Detalles Bibliográficos
Autores principales: Couvineau, Alain, Nicole, Pascal, Gratio, Valérie, Voisin, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365956/
https://www.ncbi.nlm.nih.gov/pubmed/35966051
http://dx.doi.org/10.3389/fendo.2022.931970