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The Etiology and Molecular Mechanism Underlying Smooth Muscle Phenotype Switching in Intimal Hyperplasia of Vein Graft and the Regulatory Role of microRNAs

Mounting evidence suggests that the phenotypic transformation of venous smooth muscle cells (SMCs) from differentiated (contractile) to dedifferentiated (proliferative and migratory) phenotypes causes excessive proliferation and further migration to the intima leading to intimal hyperplasia, which r...

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Detalles Bibliográficos
Autores principales: Zhang, Dengshen, Cao, Yiran, Liu, Daxing, Zhang, Jian, Guo, Yingqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365958/
https://www.ncbi.nlm.nih.gov/pubmed/35966541
http://dx.doi.org/10.3389/fcvm.2022.935054