Abnormal B-Cell Maturation and Increased Transitional B Cells in CBL Syndrome

CBL syndrome is a Noonan-like RASopathy with heterogeneous clinical phenotype and predisposition to juvenile myelomonocytic leukemia (JMML). Here we describe two patients with identical germline CBL mutation and clinical and immune-hematological overlapping features with autoimmune lymphoproliferati...

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Detalles Bibliográficos
Autores principales: Saettini, Francesco, Coliva, Tiziana Angela, Vendemini, Francesca, Galbiati, Marta, Bugarin, Cristina, Masetti, Riccardo, Moratto, Daniele, Chiarini, Marco, Guerra, Fabiola, Iascone, Maria, Badolato, Raffaele, Cazzaniga, Giovanni, Niemeyer, Charlotte, Flotho, Christian, Biondi, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366004/
https://www.ncbi.nlm.nih.gov/pubmed/35967575
http://dx.doi.org/10.3389/fped.2022.935951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366004/
https://www.ncbi.nlm.nih.gov/pubmed/35967575
http://dx.doi.org/10.3389/fped.2022.935951

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