Case report: Effectiveness of sirolimus in a de novo FAS mutation leading to autoimmune lymphoproliferative syndrome-FAS and elevated DNT/Treg ratio

BACKGROUND: The autoimmune lymphoproliferative syndrome (ALPS) is a rare disease characterized by defective function of the FAS death receptor, which results in chronic, non-malignant lymphoproliferation and autoimmunity accompanied by elevated numbers of double-negative (DN) T cells (T-cell recepto...

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Detalles Bibliográficos
Autores principales: Gu, Hao, Chen, Zhenping, Ma, Jie, Ma, Jingyao, Fu, Lingling, Zhang, Rui, Wang, Tianyou, Wu, Runhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366043/
https://www.ncbi.nlm.nih.gov/pubmed/35967554
http://dx.doi.org/10.3389/fped.2022.868193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366043/
https://www.ncbi.nlm.nih.gov/pubmed/35967554
http://dx.doi.org/10.3389/fped.2022.868193

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