Non-myeloablative conditioning is sufficient to achieve complete donor myeloid chimerism following matched sibling donor bone marrow transplant for myeloproliferative leukemia virus oncogene (MPL) mutation-driven congenital amegakaryocytic thrombocytopenia: Case report

BACKGROUND: Congenital amegakaryocytic thrombocytopenia (CAMT) is a rare platelet production disorder caused mainly by loss of function biallelic mutations in myeloproliferative leukemia virus oncogene (MPL), the gene encoding the thrombopoietin receptor (TPOR). Patients with MPL-mutant CAMT are not...

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Detalles Bibliográficos
Autores principales: Oved, Joseph Hai, Shah, Yash B., Venella, Kimberly, Paessler, Michele E., Olson, Timothy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366100/
https://www.ncbi.nlm.nih.gov/pubmed/35967582
http://dx.doi.org/10.3389/fped.2022.903872

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366100/
https://www.ncbi.nlm.nih.gov/pubmed/35967582
http://dx.doi.org/10.3389/fped.2022.903872

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