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Immunological and prognostic analysis of PSENEN in low-grade gliomas: An immune infiltration-related prognostic biomarker

Metformin is widely used in the treatment of type 2 diabetes (T2D) and plays a role in antitumor and antiobesity processes. A recent study identified its direct molecular target, PEN2 (PSENEN). PSENEN is the minimal subunit of the multiprotein complex γ-secretase, which promotes the differentiation...

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Detalles Bibliográficos
Autores principales: Chen, Kaijie, Liang, Beibei, Ma, Wenhao, Wan, Guoqing, Chen, Bing, Lu, Changlian, Luo, Yuzhou, Gu, Xuefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366120/
https://www.ncbi.nlm.nih.gov/pubmed/35966015
http://dx.doi.org/10.3389/fnmol.2022.933855