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Novel splice-site variants c.393G>A, c.278_2A>G in exon 2 and Q705K variant in exon 3 of NLRP3 gene are associated with bipolar I disorder

NOD-like receptor pyrin domain-containing 3 (NLRP3) has been considered to play a crucial role in triggering the host's immune and inflammatory responses. Genetic variants are critical determinants of interindividual variances in inflammatory responses and clinical outcomes. The role of NLRP3 g...

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Detalles Bibliográficos
Autores principales: Öztürk, Kuyaş Hekimler, ünal, Gülin Özdamar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366148/
https://www.ncbi.nlm.nih.gov/pubmed/35920179
http://dx.doi.org/10.3892/mmr.2022.12810