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Decreased RNA-binding protein IGF2BP2 downregulates NT5DC2, which suppresses cell proliferation, and induces cell cycle arrest and apoptosis in diffuse large B-cell lymphoma cells by regulating the p53 signaling pathway
Diffuse large B-cell lymphoma (DLBCL) remains difficult to treat clinically due to its highly aggressive characteristics. Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) and 5′-nucleotidase domain-containing 2 (NT5DC2) have been suggested as potential regulators in numerous types of ca...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366151/ https://www.ncbi.nlm.nih.gov/pubmed/35894142 http://dx.doi.org/10.3892/mmr.2022.12802 |