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Emerging translational strategies and challenges for enhancing regulatory T cell therapy for graft-versus-host disease

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a curative therapy for many types of cancer. Genetic disparities between donor and host can result in immune-mediated attack of host tissues, known as graft versus host disease (GVHD), a major cause of morbidity and mortality followin...

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Detalles Bibliográficos
Autores principales: Hippen, Keli L., Hefazi, Mehrdad, Larson, Jemma H., Blazar, Bruce R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366169/
https://www.ncbi.nlm.nih.gov/pubmed/35967386
http://dx.doi.org/10.3389/fimmu.2022.926550