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NAT10 promotes cell proliferation by acetylating CEP170 mRNA to enhance translation efficiency in multiple myeloma

Multiple myeloma (MM) is still an incurable hematologic malignancy, which is eagerly to the discovery of novel therapeutic targets and methods. N-acetyltransferase 10 (NAT10) is the first reported regulator of mRNA acetylation that is activated in many cancers. However, the function of NAT10 in MM r...

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Detalles Bibliográficos
Autores principales: Wei, Rongfang, Cui, Xing, Min, Jie, Lin, Zigen, Zhou, Yanyan, Guo, Mengjie, An, Xiaojuan, Liu, Hao, Janz, Siegfried, Gu, Chunyan, Wang, Hongbo, Yang, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366180/
https://www.ncbi.nlm.nih.gov/pubmed/35967285
http://dx.doi.org/10.1016/j.apsb.2022.01.015